Founded December 2016
Stage Technology development
Investor Trendlines Incubators Israel
CEO Ofer Levy
ZygoFix has developed a unique screw-less implant for spinal fusion, a frequent surgical procedure prescribed for severe back pain.
ZygoFix’s zLOCK system is based on a miniature 3D-printed implant that achieves spinal fusion and spinal stability without screws.
Today, the standard fusion procedure utilizes a 30-year old technology that involves placing large pedicle screws and a short rod in the treated segment for spinal stability. The purpose of the pedicle screw construct is to form a solid bridge between adjacent vertebrae as a form of stabilization. The procedure is complex, screws and rods are invasive, and complications may occur if screws are misplaced
With zLOCK, the surgeon utilizes the natural construction of the vertebrae to provide spinal stability and eliminates the need to construct a bridge with pedicle screws and a rod. The zLOCK procedure is less invasive (1 incision per side), simple, straight forward and can be performed in an outpatient setting.
The zLOCK system is a winner of the 2017 Spine Technology awards, 2019 GOLD winner of MassChallenge Israel and is in clinical phase with promising initial results.
Due to its unique design and placement, zLOCK provides numerous advantages:
Learn more about how ZyogFix meets the market needs in this Q&A with CEO Ofer Levy.
3 granted patents
Jerusalem Post (2018): ISRAELI MED-TECH STARTUP AIMS TO END CHRONIC BACK PAIN
The market seeks an improved minimally invasive solution for spinal fusion that is simpler and less invasive, minimizes trauma, and affords greater efficacy. ZygoFix’s zLOCK meets these market needs.
See the interview with CEO Ofer Levy on ILTV.
15+ years experience in the medical device industry as an engineer, product manager, and consultant; deep understanding of medical device development and life cycle; Former VP, Qsite Quality and Regulatory; MBA Tel Aviv University; BSc, mechanical engineering, Ben-Gurion University of the Negev
Serial medical entrepreneur; 30 years’ experience in medical device industry; 26 issued patents and 39+ pending (all in spine); former CTO Impliant (world’s first facet replacement device), CTO Spine 21 (world’s first remote-controlled spinal implant), founder and CTO ApiFix
Chairman and Director of the Israel Spine Center, Assuta Hospital, Tel Aviv; former Chief of Spine Surgery, Hadassah Hebrew University Medical Center, Jerusalem, President of the Israel Orthopedic Association, member of numerous organizations, including Scoliosis Research Society, International Society for the Study of the Lumbar Spine, Spine Society of Europe, and the North American Spine Society
Spinal fusion is one of the most common surgical procedures – fifth in terms of OR time consumption (HCUP Statistical Brief #186).
The zLOCK system is suitable for 3 types of spinal fusion applications: lumbar fusion, SI (sacroiliac) fusion, and cervical fusion. The addressable market for zLOCK surpasses US$2 billion with more than 700,000 applicable procedures.